A lawyer or other non-specialist may be impressed by the clever invention described in the IsNot application, but each first-year computer science student will recognize what it is about: this is the inequality operator between pointer values as is known from many different programming languages ranging from the Branch Not Equal instruction BNE in PDP11 assembly language  to the not equal operator .NE. in Fortran  or the not equal operator != in C , Java  or C# .
For a computer scientist, the idea of having a single operator for comparing two pointer values is common knowledge and the publications cited above constitute prior art.
For a computer scientist, granting this patent application will have devastating effects since it will cover a large majority of the software worldwide and will completely block any further software development or at least dramatically increase developments costs due to licensing.
In a strict sense, the claims in this patent application are non-novel and they are anticipated by prior art. Colloquially, this would be called a trivial patent.